Issue 16, 2021
From the journal:

Organic Chemistry Frontiers

Recent advances of Ritter reaction and its synthetic applications

Meng-En Chen,†a   Xiao-Wei Chen,†a   Yue-Hong Hu,†a   Rui Ye,a   Jian-Wei Lv,a   Baosheng Li ORCID logo *b  and  Fu-Min Zhang ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry & College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China
E-mail: zhangfm@lzu.edu.cn

b School of Chemistry and Chemical Engineering, Chongqing University, 174 Shazheng Street, Chongqing, P. R. China
E-mail: libs@cqu.edu.cn

Abstract

In comparison to previous reviews, the present review article provides a comprehensive survey of Ritter reactions from 2014 to 2020, mainly aiming to discuss diverse Ritter reactions and their widely synthetic applications. Notably, the oxidative Ritter-type reactions are presented for the first time, and tandem Ritter reactions and asymmetric Ritter reactions are also highlighted. Furthermore, the systematic summary of the application of Ritter reactions in the total synthesis of natural products and the preparation of drugs, bioactive compounds, and functional molecules is introduced.

Graphical abstract: Recent advances of Ritter reaction and its synthetic applications

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Article information

DOI
https://doi.org/10.1039/D1QO00496D
Article type
Review Article
Submitted
31 Mar 2021
Accepted
10 May 2021
First published
12 May 2021

Org. Chem. Front., 2021,8, 4623-4664

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Recent advances of Ritter reaction and its synthetic applications

M. Chen, X. Chen, Y. Hu, R. Ye, J. Lv, B. Li and F. Zhang, Org. Chem. Front., 2021, 8, 4623 DOI: 10.1039/D1QO00496D

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