Recent advances in electrochemically driven radical fluorination and fluoroalkylation

Abstract

Electrochemical fluorination (ECF) refers to the introduction of fluorine-containing moieties into organic molecules under electrochemical conditions. The primary objective of this review is to provide the reader with the highlights of electron-induced radical fluorinations in the past decade, comprising fluorination, difluoromethylation, trifluoromethylation and perfluoroalkylation. Some representative mechanisms are outlined for researchers to gain insight in the basic principles behind this technology.