Electrochemical tandem trifluoromethylation of allylamines/formal (3 + 2)-cycloaddition for the rapid access to CF3-containing imidazolines and oxazolidines

Abstract

An electrochemical tandem radical trifluoromethylation of allylamines/formal (3 + 2)-cycloaddition with nitrile and carbonyl compounds has been developed under mild and environmentally benign reaction conditions. Such multicomponent reaction allowed the construction of CF₃-containing imidazolines and oxazolidines by creating three new bonds from simple and easily available starting materials.