Wen-Xiu Lu, Jian Xing, Yijia Sun, Qinge Huang, Zhenwei Deng and Jian-Gang Mao
Org. Biomol. Chem., 2021,19, 10210-10214
DOI:
10.1039/D1OB01996A,
Paper
Catalytic carbonyl formation ranks as one of the most important synthetic methodologies. Herein, a highly effective palladium-catalyzed and alcohol-promoted transformation of nitriles to synthesize benzocyclic ketones is described. It provides a straightforward access to potentially valuable indanone compounds in high yields in the presence of alcohol. It avoided the usage of carbon monoxide or an additional hydrolysis procedure.
