Issue 39, 2021

Hydrophilic and hydrophobic carboxamide pincers as anion hosts

Abstract

Hydrophobic and hydrophilic, monotopic and ditopic carboxamide pincer hosts containing ethyl, hexyl, 2-hydroxyethyl and 2-hydroxyethyl ethyl ether pendant arms were synthesized. Solubility trends indicated that solubilities in water or hydrocarbon solvents varied depending on the nature of the pendant arms. Binding constants for hydrophilic pincers were larger in general than their hydrophobic analogs. Significant synergistic binding effects for the ditopic hosts were not observed.

Graphical abstract: Hydrophilic and hydrophobic carboxamide pincers as anion hosts

Supplementary files

Article information

Article type
Communication
Submitted
15 Aug 2021
Accepted
06 Sep 2021
First published
09 Sep 2021

Org. Biomol. Chem., 2021,19, 8516-8520

Author version available

Hydrophilic and hydrophobic carboxamide pincers as anion hosts

J. Lohrman, S. Pramanik, S. Kaur, H. Telikepalli, V. W. Day and K. Bowman-James, Org. Biomol. Chem., 2021, 19, 8516 DOI: 10.1039/D1OB01605A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements