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Issue 8, 2021
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A palladium-catalyzed cascade process for spirooxindole: an alternative way for the synthesis of spiro(indoline-3,2′-quinazolin)-2-ones

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Abstract

A palladium-catalyzed cascade strategy has been developed for one-pot synthesis of functionalized spiro(indoline-3,2′-quinazolin)-2-one derivatives from readily available starting materials. The reaction proceeds via C–C and two C–N bond formations in a single reaction operation. This method offers an attractive pathway for the synthesis of a broad range of spiro(indoline-3,2′-quinazolin)-2-ones in good yields.

Graphical abstract: A palladium-catalyzed cascade process for spirooxindole: an alternative way for the synthesis of spiro(indoline-3,2′-quinazolin)-2-ones

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Article information


Submitted
28 Dec 2020
Accepted
26 Jan 2021
First published
09 Feb 2021

Org. Biomol. Chem., 2021,19, 1795-1806
Article type
Paper

A palladium-catalyzed cascade process for spirooxindole: an alternative way for the synthesis of spiro(indoline-3,2′-quinazolin)-2-ones

A. Sharma, D. Dutta and P. Gogoi, Org. Biomol. Chem., 2021, 19, 1795
DOI: 10.1039/D0OB02580A

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