Lingfei Duan, Kai Jiang, Hua Zhu and Biaolin Yin
Org. Biomol. Chem., 2021,19, 365-369
DOI:
10.1039/D0OB02037K,
Communication
A CuH-catalyzed Z-selective partial reduction of alkynyl amides to afford α,β-unsaturated amides using silane as the hydrogen donor is developed. This reaction is carried out under mild conditions and able to accommodate a broad scope of alkynyl amides including those bearing a terminal carbon–carbon double bond or triple bond, affording alkenyl amides with high stereoselectivity and excellent yields.
