Issue 1, 2021

Catalytic polymersomes to produce strong and long-lasting bioluminescence

Abstract

Here, we introduce an artificial bioluminescent nanocompartment based on the encapsulation of light-producing enzymes, luciferases, inside polymersomes. We exploit nanocompartmentalization to enhance luciferase stability in a cellular environment but also to positively modulate enzyme kinetics to achieve a long-lasting glow type signal. These features pave the way for expanding bioluminescence to nanotechnology-based applications.

Graphical abstract: Catalytic polymersomes to produce strong and long-lasting bioluminescence

Supplementary files

Article information

Article type
Communication
Submitted
07 Oct 2020
Accepted
14 Dec 2020
First published
14 Dec 2020
This article is Open Access
Creative Commons BY-NC license

Nanoscale, 2021,13, 66-70

Catalytic polymersomes to produce strong and long-lasting bioluminescence

C. E. Meyer, I. Craciun, C. Schoenenberger, R. Wehr and C. G. Palivan, Nanoscale, 2021, 13, 66 DOI: 10.1039/D0NR07178A

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