A novel fast-responsive fluorescent probe based on 1,3,5-triazine for endogenous H2S detection with large Stokes shift and its application in cell imaging

Zhi-Hao Zhang; Shaoqing Li; Yizhe Yan; Jianbo Qu; Jian-Yong Wang

doi:10.1039/D1NJ01319J

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A novel fast-responsive fluorescent probe based on 1,3,5-triazine for endogenous H₂S detection with large Stokes shift and its application in cell imaging†

Zhi-Hao Zhang,‡^a Shaoqing Li,‡^b Yizhe Yan,

*^b Jianbo Qu^a and Jian-Yong Wang

*^a

Author affiliations

* Corresponding authors

^a School of Light Industry and Engineering, Qi Lu University of Technology (Shandong Academy of Sciences), Jinan, P. R. China
E-mail: wjy@qlu.edu.cn

^b College of Food and Bioengineering, Henan Key Laboratory of Cold Chain Food Quality and Safety Control, Zhengzhou University of Light Industry, Zhengzhou, P. R. China
E-mail: yanyizhe@mail.ustc.edu.cn

Abstract

A novel fast-responsive fluorescent probe TzAr-H2S was constructed to realize the imaging of endogenous H₂S in living cells. This turn-on fluorescent probe TzAr-H2S can quickly (only 20 s) detect H₂S with good selectivity, large Stokes shift (100 nm) and low cytotoxicity, which might provide a powerful tool for understanding the regulation mechanism of hydrogen sulfide in cells.

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Supplementary information PDF (1018K)

Article information

DOI: https://doi.org/10.1039/D1NJ01319J
Article type: Communication
Submitted: 18 Mar 2021
Accepted: 12 May 2021
First published: 13 May 2021

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New J. Chem., 2021,45, 9756-9760

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A novel fast-responsive fluorescent probe based on 1,3,5-triazine for endogenous H₂S detection with large Stokes shift and its application in cell imaging

Z. Zhang, S. Li, Y. Yan, J. Qu and J. Wang, New J. Chem., 2021, 45, 9756 DOI: 10.1039/D1NJ01319J

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