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Issue 2, 2021
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Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation

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Abstract

Cell-imprinted substrates direct stem cell differentiation into various lineages, suggesting the idea of lineage-specific nanotopography. We herein examined the surface topography of five different imprinted cell patterns using AFM imaging and statistical analysis of amplitude, spatial, and hybrid roughness parameters. The results suggest that different cell imprints possess distinguished nanotopographical features.

Graphical abstract: Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation

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Supplementary files

Article information


Submitted
21 Aug 2020
Accepted
01 Dec 2020
First published
08 Dec 2020

This article is Open Access

Nanoscale Adv., 2021,3, 333-338
Article type
Communication

Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation

K. Kamguyan, S. Zajforoushan Moghaddam, A. Nazbar, S. M. A. Haramshahi, S. Taheri, S. Bonakdar and E. Thormann, Nanoscale Adv., 2021, 3, 333
DOI: 10.1039/D0NA00692K

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