Issue 36, 2021
From the journal:

Chemical Communications

Enantioselective nickel-catalyzed anti-arylmetallative cyclizations onto acyclic electron-deficient alkenes†

Simone M. Gillbard,ab   Harley Green,ab   Stephen P. Argent ORCID logo ‡b  and  Hon Wai Lam ORCID logo *ab  

* Corresponding authors

a The GlaxoSmithKline Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Jubilee Campus, Triumph Road, Nottingham, UK
E-mail: hon.lam@nottingham.ac.uk

b School of Chemistry, University of Nottingham, University Park, Nottingham, UK

Abstract

Enantioselective nickel-catalyzed reactions of (hetero)arylboronic acids or alkenylboronic acids with substrates containing an alkyne tethered to various acyclic electron-deficient alkenes are described.

Graphical abstract: Enantioselective nickel-catalyzed anti-arylmetallative cyclizations onto acyclic electron-deficient alkenes

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Article information

DOI
https://doi.org/10.1039/D1CC01166A
Article type
Communication
Submitted
03 Mar 2021
Accepted
23 Mar 2021
First published
06 Apr 2021
This article is Open Access
Creative Commons BY license

Chem. Commun., 2021,57, 4436-4439

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Enantioselective nickel-catalyzed anti-arylmetallative cyclizations onto acyclic electron-deficient alkenes

S. M. Gillbard, H. Green, S. P. Argent and H. W. Lam, Chem. Commun., 2021, 57, 4436 DOI: 10.1039/D1CC01166A

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