A PDA-DTC/Cu–MnO2 nanoplatform for MR imaging and multi-therapy for triple-negative breast cancer treatment

Xiaochun Hu; Yonglin Lu; Wenrong Zhao; Menglin Sun; Ruihao Li; Lei Feng; Tianming Yao; Chunyan Dong; Shuo Shi

doi:10.1039/D1CC00987G

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A PDA-DTC/Cu–MnO₂ nanoplatform for MR imaging and multi-therapy for triple-negative breast cancer treatment†

Xiaochun Hu,‡^a Yonglin Lu,‡^a Wenrong Zhao,^b Menglin Sun,^b Ruihao Li,^a Lei Feng,^a Tianming Yao,

^a Chunyan Dong

*^b and Shuo Shi

*^a

Author affiliations

* Corresponding authors

^a Breast Cancer Center, Shanghai East Hospital, School of Medicine, Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, P. R. China
E-mail: shishuo@tongji.edu.cn

^b Breast Cancer Center, Shanghai East Hospital, Nanjing Medical University, Shanghai 200120, P. R. China
E-mail: cy_dong@tongji.edu.cn

Abstract

Herein, a multi-functional nanoplatform (PDA-DTC/Cu–MnO₂) was established, which has been employed for MR imaging-guided multi-therapy (CDT, PTT and chemotherapy) for cancer treatment. The in vitro and in vivo results confirmed that the biocompatible nanoplatform could significantly induce tumor cell death and inhibit tumor growth.

Download options Please wait...

Supplementary files

Supplementary information PDF (1637K)

Article information

DOI: https://doi.org/10.1039/D1CC00987G
Article type: Communication
Submitted: 21 Feb 2021
Accepted: 16 Mar 2021
First published: 22 Mar 2021

Download Citation

Chem. Commun., 2021,57, 4158-4161

Permissions

Request permissions

A PDA-DTC/Cu–MnO₂ nanoplatform for MR imaging and multi-therapy for triple-negative breast cancer treatment

X. Hu, Y. Lu, W. Zhao, M. Sun, R. Li, L. Feng, T. Yao, C. Dong and S. Shi, Chem. Commun., 2021, 57, 4158 DOI: 10.1039/D1CC00987G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications