Issue 31, 2021
From the journal:

Chemical Communications

Hydrophobic collapse-driven nanoparticle coating with poly-adenine adhesives†

Dan Zhu,a   Jiang Li, ORCID logo bc   Lianhui Wang, ORCID logo a   Qian Li, ORCID logo c   Lihua Wang, ORCID logo b   Bo Song,*d   Ruhong Zhou*e  and  Chunhai Fan*c  

* Corresponding authors

a Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications, Nanjing 210023, China

b The Interdisciplinary Research Center, Shanghai Synchrotron Radiation Facility, Zhangjiang Laboratory, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China

c School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China
E-mail: fanchunhai@sjtu.edu.cn

d School of Optical-Electrical Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
E-mail: bsong@usst.edu.cn

e Institute of Quantitative Biology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China
E-mail: rhzhou@zju.edu.cn

Abstract

The mechanism underlying the strong adhesion between DNA with consecutive adenines (polyA) and Au nanoparticles (AuNPs) is experimentally and theoretically studied. We elucidate that the consecutive adenines collectively result in hydrophobic collapse in the adhesion process, which plays a pivotal role for the high adhesion affinity and specificity.

Graphical abstract: Hydrophobic collapse-driven nanoparticle coating with poly-adenine adhesives

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Article information

DOI
https://doi.org/10.1039/D1CC00628B
Article type
Communication
Submitted
03 Feb 2021
Accepted
15 Mar 2021
First published
15 Mar 2021

Chem. Commun., 2021,57, 3801-3804

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Hydrophobic collapse-driven nanoparticle coating with poly-adenine adhesives

D. Zhu, J. Li, L. Wang, Q. Li, L. Wang, B. Song, R. Zhou and C. Fan, Chem. Commun., 2021, 57, 3801 DOI: 10.1039/D1CC00628B

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