A new route to azocines and benzoazocines from furopyridinones is described through a photochemically induced [1,3]-sigmatropic rearrangement. The method gives access to these 8-membered nitrogen heterocycles from dimethyl squarate in four stages and with excellent atom economy by sequencing thermal and photochemical ring expansion steps under continuous flow.
![Graphical abstract: A photochemical ring expansion of 6- to 8-membered nitrogen heterocycles by [1,3]-sigmatropic rearrangement](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=D1CC00393C&imageInfo.ImageIdentifier.Year=2021)
M. A. Manning, W. Sun, M. E. Light and D. C. Harrowven, Chem. Commun., 2021, 57, 4556 DOI: 10.1039/D1CC00393C
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