Jump to main content
Jump to site search

Issue 42, 2021
Previous Article Next Article

Chemiluminescent self-reported unfolding of single-chain nanoparticles

Author affiliations

Abstract

We demonstrate the light-induced, crosslinker mediated collapse of linear polymer chains into single-chain nanoparticles (SCNPs) capable of self-reporting their unfolding. The crosslinker entails a phenyloxalate motif allowing for the targeted degradation of the SCNPs via addition of hydrogen peroxide that triggers chemiluminescence (CL). The time-dependant CL emission can serve as a guide to follow the time dependent unfolding of the SCNPs, allowing for a qualitative assessment of the underlying mechanism.

Graphical abstract: Chemiluminescent self-reported unfolding of single-chain nanoparticles

Back to tab navigation

Supplementary files

Article information


Submitted
06 Jan 2021
Accepted
20 Apr 2021
First published
20 Apr 2021

Chem. Commun., 2021,57, 5203-5206
Article type
Communication

Chemiluminescent self-reported unfolding of single-chain nanoparticles

F. R. Bloesser, S. L. Walden, I. M. Irshadeen, L. C. Chambers and C. Barner-Kowollik, Chem. Commun., 2021, 57, 5203
DOI: 10.1039/D1CC00068C

Social activity

Search articles by author

Spotlight

Advertisements