Clues from cocrystals: a ternary solid, polymorphism, and rare supramolecular isomerism involving resveratrol and 5-fluorouracil

Abstract

We describe a supramolecular synthesis of a ternary cocrystal involving resveratrol and 5-fluorouracil (5-fu) with trans-bis(4-pyridyl)ethylene (bpe). We also have discovered a polymorph of a binary cocrystal involving 5-fu and bpe that originates from rare supramolecular isomerism.