Jump to main content
Jump to site search

Issue 3, 2021
Previous Article Next Article

TMSCFX2 (X = Cl, Br) as halofluorocarbene sources for the synthesis of halofluorocyclopropanes

Author affiliations

Abstract

TMSCFX2 (X = Cl, Br; TMS = trimethylsilyl) have been developed as halofluorocarbene (CFX, X = Cl, Br) precursors for [2+1] cyclopropanation with alkenes. Structurally diverse halofluorocyclopropanes were obtained in good to excellent yields. It was found that the reactivity order of the three halofluorocarbene reagents (TMSCF2Br, TMSCFCl2, and TMSCFBr2) in halofluorocyclopropanation with 1,1-diphenylethylene can be very different under different reaction conditions.

Graphical abstract: TMSCFX2 (X = Cl, Br) as halofluorocarbene sources for the synthesis of halofluorocyclopropanes

Back to tab navigation

Supplementary files

Article information


Submitted
05 Sep 2020
Accepted
02 Dec 2020
First published
08 Dec 2020

Chem. Commun., 2021,57, 319-322
Article type
Communication

TMSCFX2 (X = Cl, Br) as halofluorocarbene sources for the synthesis of halofluorocyclopropanes

D. Chen, Z. Fan, L. Huang, K. Gao, P. Xiao, C. Ni and J. Hu, Chem. Commun., 2021, 57, 319
DOI: 10.1039/D0CC06004F

Social activity

Search articles by author

Spotlight

Advertisements