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Issue 7, 2021
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Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

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Abstract

Using the children's toy, Shrinky-Dink©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 1 ag mL−1 of the S1 subunit of the spike protein.

Graphical abstract: Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

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Article information


Submitted
08 Jan 2021
Accepted
02 Feb 2021
First published
12 Feb 2021

Anal. Methods, 2021,13, 874-883
Article type
Communication

Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

J. A. Zakashansky, A. H. Imamura, D. F. Salgado, H. C. Romero Mercieca, R. F. L. Aguas, A. M. Lao, J. Pariser, N. Arroyo-Currás and M. Khine, Anal. Methods, 2021, 13, 874
DOI: 10.1039/D1AY00041A

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