Regulating Metal-Organic Frameworks as Stationary Phases and Absorbents for Analytical Separations
Metal-organic frameworks (MOFs) are highly ordered framework systems composed of metal centers and organic linkers through coordination bonds. The diversity of metal elements and easily modified organic ligands, together with controllable synthetic approaches, give rise to the designability of MOFs structure and topology and make MOFs able to be functionalized. The structural diversity provides MOFs with many unique properties, such as permanent porosity, flexible structures, thermostability, and high adsorption capacity, leading to great practicability in technical applications. In this review, we concentrated on the applications of MOFs in the field of gas chromatography, high-performance liquid chromatography, and enrichment of biomolecules, based on the rational arrangement in structures and functions of MOFs. Moreover, we emphasized the importance of structural and chemical regulations for the improvement of separation efficiency.
- This article is part of the themed collection: Analytical Methods HOT Articles 2021