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Recent advances in total syntheses of natural products containing the benzocycloheptane motif

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Abstract

Covering: 2010 to 2020

Benzocycloheptane is a fundamental and unique structural motif found in pharmaceuticals and natural products. The total syntheses of natural products bearing the benzocycloheptane subunit are challenging and there are only a few efficient approaches to access benzocycloheptane. Thus, new methods and innovative strategies for preparing such natural products need to be developed. In this review, recent progress in the total syntheses of natural products bearing the benzocycloheptane motif is presented, and key transformations for the construction of benzocycloheptane are highlighted. This review provides a useful guide for those engaged in the syntheses of natural products containing the benzocycloheptane motif.

Graphical abstract: Recent advances in total syntheses of natural products containing the benzocycloheptane motif

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Article information


Submitted
05 Jan 2021
First published
02 Mar 2021

Nat. Prod. Rep., 2021, Advance Article
Article type
Review Article

Recent advances in total syntheses of natural products containing the benzocycloheptane motif

J. Fan, Y. Hu, L. Li, J. Wang, S. Li, J. Zhao and C. Li, Nat. Prod. Rep., 2021, Advance Article , DOI: 10.1039/D1NP00003A

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