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Issue 4, 2021
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Elimination of aliasing in LA-ICP-MS by alignment of laser and mass spectrometer

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Abstract

Insufficient sampling of periodic signals results in an unwanted phenomenon known as aliasing. When measuring by LA-ICP-MS it is widely observed that aliasing between laser pulse rates and sampling by sequential ICP-MS instruments creates erroneous variations in the measured element concentrations in the sample. Smoothing the sample flow to the ICP-MS can largely eliminate this variation but reduces spatial resolution of the time-resolved signal and is thus detrimental for imaging with the increasingly popular fast response sample cells. We have developed a fire control circuit that fires the laser in alignment with the measurement cycle of the mass spectrometer to lessen or eliminate aliasing. We describe the device and show that with a conventional quadrupole ICP-MS the technique is able to maintain measurement precision when the extent of mixing between individual laser pulses is reduced by an order of magnitude.

Graphical abstract: Elimination of aliasing in LA-ICP-MS by alignment of laser and mass spectrometer

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Article information


Submitted
25 Nov 2020
Accepted
18 Feb 2021
First published
23 Feb 2021

J. Anal. At. Spectrom., 2021,36, 733-739
Article type
Technical Note

Elimination of aliasing in LA-ICP-MS by alignment of laser and mass spectrometer

C. A. Norris, L. Danyushevsky, P. Olin and N. R. West, J. Anal. At. Spectrom., 2021, 36, 733
DOI: 10.1039/D0JA00488J

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