Issue 8, 2021

Revealing the antiaging effects of cereal- and food oil-derived active substances by a Caenorhabditis elegans model

Abstract

Cereal grains and oils contain various functional ingredients, such as amino acids, peptides, polyphenols, dietary fiber, linoleic acid, and natural pigments. Their biological activities are of great significance. Benefiting from its robust genetic function and simple cultivation, Caenorhabditis elegans, as one of the most important model organisms has been widely used to screen antiaging substances and investigate the underlying molecular mechanisms. In this paper, the recent advances in the use of C. elegans in antiaging research into active substances from cereals and oils will be assessed, and their potential signal transduction mechanisms will be systematically reviewed. This research aims to provide a theoretical reference for the use of active substances from cereals and oils to prevent and delay aging and aging-associated diseases.

Graphical abstract: Revealing the antiaging effects of cereal- and food oil-derived active substances by a Caenorhabditis elegans model

Article information

Article type
Review Article
Submitted
25 Aug 2020
Accepted
26 Feb 2021
First published
09 Mar 2021

Food Funct., 2021,12, 3296-3306

Revealing the antiaging effects of cereal- and food oil-derived active substances by a Caenorhabditis elegans model

D. Xu, Q. Lin, W. Wu, Y. Wu and Y. Liang, Food Funct., 2021, 12, 3296 DOI: 10.1039/D0FO02240C

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