Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines†
The investigation of microbiome-derived metabolites is important to understand metabolic interactions with their human host. New methodologies for mass spectrometric discovery of undetected metabolites with unknown bioactivity are required. Herein, we introduce squaric acid as a new chemoselective moiety for amine metabolite analysis in human fecal samples.
- This article is part of the themed collection: Analytical methods in chemical biology