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Issue 8, 2021
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The role of poly(2-alkyl-2-oxazoline)s in hydrogels and biofabrication

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Abstract

Poly(2-alkyl-2-oxazoline)s (PAOXAs) have been rapidly emerging as starting materials in the design of tissue engineering supports and for the generation of platforms for cell cultures, especially in the form of hydrogels. Thanks to their biocompatibility, chemical versatility and robustness, PAOXAs now represent a valid alternative to poly(ethylene glycol)s (PEGs) and their derivatives in these applications, and in the formulation of bioinks for three-dimensional (3D) bioprinting. In this review, we summarize the recent literature where PAOXAs have been used as main components for hydrogels and biofabrication mixtures, especially highlighting how their easily tunable composition could be exploited to fabricate multifunctional biomaterials with an extremely broad spectrum of properties.

Graphical abstract: The role of poly(2-alkyl-2-oxazoline)s in hydrogels and biofabrication

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Article information


Submitted
30 Dec 2020
Accepted
16 Feb 2021
First published
22 Feb 2021

This article is Open Access

Biomater. Sci., 2021,9, 2874-2886
Article type
Minireview

The role of poly(2-alkyl-2-oxazoline)s in hydrogels and biofabrication

L. Trachsel, M. Zenobi-Wong and E. M. Benetti, Biomater. Sci., 2021, 9, 2874
DOI: 10.1039/D0BM02217A

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