Jump to main content
Jump to site search


One-pot Synthesis of Multifunctional Bi2S3 Nanoparticles and Construction of Core-shell Bi2S3@-Ce6-CeO2 Nanocomposites for NIR-Triggered Phototherapy

Abstract

As a direct thin band gap n-type semiconductor, bismuth sulfide (Bi2S3) nanomaterial possesses great near-infrared (NIR) triggered photothermal effect, photoacoustic (PA) and computed tomography (CT) imaging property. Hence, Bi2S3 nanomaterial has become a research hotpot in multiple domains, such as the construction of NIR-triggered nanosystems for cancer therapy. In this paper, through simply one-pot synthesis with the assistance of EDTA-2Na, we first got monodisperse spherical Bi2S3 of uniform particle size with fascinating photothermal and PA/CT imaging property. Based on this, we introduced photosensitizer Ce6 with photodynamic property and CeO2 with the O2-evolving characteristic, thus designed a core-shell structure of Bi2S3@-Ce6-CeO2 nanocomposites (Bi2S3@-Ce6-CeO2 NCs). The as received Bi2S3@-Ce6-CeO2 NCs exhibited remarkable synergetic photothermal and photodynamic therapeutic effect both in vitro and vivo, demonstrating its promising potential for cancer treatments. In the long term, the multifunctional PA/CT properties of both Bi2S3 NPs and Bi2S3@-Ce6-CeO2 NCs in this study also supply a novel Bi2S3-basing platform for constructing integrated diagnosis and treatment platforms..

Back to tab navigation

Supplementary files

Article information


Submitted
10 Jan 2020
Accepted
18 Mar 2020
First published
20 Mar 2020

J. Mater. Chem. B, 2020, Accepted Manuscript
Article type
Paper

One-pot Synthesis of Multifunctional Bi2S3 Nanoparticles and Construction of Core-shell Bi2S3@-Ce6-CeO2 Nanocomposites for NIR-Triggered Phototherapy

L. Zeng, H. Zhao, Y. Zhu, S. Chen, Y. Zhang, D. Wei, J. Sun and H. Fan, J. Mater. Chem. B, 2020, Accepted Manuscript , DOI: 10.1039/D0TB00080A

Social activity

Search articles by author

Spotlight

Advertisements