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Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

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Abstract

Ultrasensitive and highly accurate bioassays are critically required for the early detection of various biomarkers and diagnosis of cancer. Electrogenerated chemiluminescence (ECL) is one such technique which shows powerful analytical ability by incorporating ECL active species for sensitive detection of targets. In this regard, the development of ECL as an assay technique is constantly being pushed for better performance and lower detection limits. Incorporation of sensitive immunosensing and aptasensing methods with ECL has the ability to multiply the advantages several-fold. The recent progress in and methods utilized for the enhancement and amplification of ECL detection techniques based on highly sensitive immunosensors and aptasensors have been discussed in this review with regard to widely popular techniques.

Graphical abstract: Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

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Article information


Submitted
15 Nov 2019
Accepted
03 Feb 2020
First published
04 Feb 2020

J. Mater. Chem. B, 2020, Advance Article
Article type
Review Article

Enhanced biosensing strategies using electrogenerated chemiluminescence: recent progress and future prospects

R. A. Husain, S. R. Barman, S. Chatterjee, I. Khan and Z. Lin, J. Mater. Chem. B, 2020, Advance Article , DOI: 10.1039/C9TB02578B

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