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A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability

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Abstract

A novel dual-targeted CeO2–DNA nanosensor by modifying with folic acid (FA) and CD36 antibody was designed. This fluorescent nanosensor enables noninvasive imaging of alterations in H2O2 in vitro and in vivo with good sensitivity and selectivity, accurately evaluating the inflammation level and providing early warning of plaque vulnerability.

Graphical abstract: A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability

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Article information


Submitted
03 Nov 2019
Accepted
09 Dec 2019
First published
10 Dec 2019

J. Mater. Chem. B, 2020, Advance Article
Article type
Communication

A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability

Z. Liu, Y. Cao, X. Zhang, H. Yang, Y. Zhao, W. Gao and B. Tang, J. Mater. Chem. B, 2020, Advance Article , DOI: 10.1039/C9TB02459J

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