Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 21st October 2020 from 07:00 AM to 07:00 PM (BST).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 9, 2020
Previous Article Next Article

Evolution of flow-oriented design strategies in the continuous preparation of pharmaceuticals

Author affiliations

Abstract

The dynamic progress in the multi-step continuous-flow synthesis of active pharmaceutical ingredients is part of the current industrial revolution. The recently implemented examples are the forerunners of safer and more sustainable pharmaceutical manufacturing. These systems utilize interconnected flow apparatuses, integrated with in-line work-up, purification and analysis. Challenging targets call for customized, flow-oriented designs to establish novel, telescoped continuous-flow sequences. In this review we focus on these efforts towards the development of uninterrupted continuous-flow systems.

Graphical abstract: Evolution of flow-oriented design strategies in the continuous preparation of pharmaceuticals

Back to tab navigation

Article information


Submitted
30 Jun 2020
Accepted
17 Jul 2020
First published
17 Jul 2020

React. Chem. Eng., 2020,5, 1527-1555
Article type
Review Article

Evolution of flow-oriented design strategies in the continuous preparation of pharmaceuticals

Z. Fülöp, P. Szemesi, P. Bana, J. Éles and I. Greiner, React. Chem. Eng., 2020, 5, 1527
DOI: 10.1039/D0RE00273A

Social activity

Search articles by author

Spotlight

Advertisements