Jump to main content
Jump to site search


A practical ortho-acylation of aryl iodides enabled by moisture-insensitive activated esters via palladium/norbornene catalysis

Author affiliations

Abstract

A novel ortho-arene C–H acylation of aryl iodides catalyzed by the palladium/norbornene cooperative system by employing triazine esters has been developed, leading to the synthesis of polysubstituted aryl ketones. This ortho-acylation even proceeds smoothly in water. Preliminary mechanistic experiments indicate that the strong electron-withdrawing ability and coordination chemistry of triazine play crucial roles in this transformation.

Graphical abstract: A practical ortho-acylation of aryl iodides enabled by moisture-insensitive activated esters via palladium/norbornene catalysis

Back to tab navigation

Supplementary files

Article information


Submitted
14 Aug 2020
Accepted
20 Sep 2020
First published
21 Sep 2020

Org. Chem. Front., 2020, Advance Article
Article type
Research Article

A practical ortho-acylation of aryl iodides enabled by moisture-insensitive activated esters via palladium/norbornene catalysis

Y. Feng, Y. Wang, S. Zhao, D. Zhang, X. Li, H. Liu, Y. Dong and F. Sun, Org. Chem. Front., 2020, Advance Article , DOI: 10.1039/D0QO00982B

Social activity

Search articles by author

Spotlight

Advertisements