Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Efficiently diastereoselective synthesis of functionalized hydro-carbazoles by base-mediated tandem annulation of 1-(2-amino-aryl)prop-2-en-1-ones and sulfur ylide

Author affiliations

Abstract

The base-promoted [3 + 3]/[1 + 4] tandem reaction of tosyl-protected o-amino α,β-unsaturated ketones and crotonate-derived sulfur ylide for the efficiently diastereoselective synthesis of functionalized hydrocarbazoles is reported. The reaction proceeded smoothly and gave the desired products in high yields and excellent diastereoselectivities under mild conditions. The hydrocarbazoles could be readily transformed into functionalized carbazoles.

Graphical abstract: Efficiently diastereoselective synthesis of functionalized hydro-carbazoles by base-mediated tandem annulation of 1-(2-amino-aryl)prop-2-en-1-ones and sulfur ylide

Back to tab navigation

Supplementary files

Article information


Submitted
04 Apr 2020
Accepted
10 May 2020
First published
11 May 2020

Org. Chem. Front., 2020, Advance Article
Article type
Research Article

Efficiently diastereoselective synthesis of functionalized hydro-carbazoles by base-mediated tandem annulation of 1-(2-amino-aryl)prop-2-en-1-ones and sulfur ylide

C. Wang, J. Zhang, Z. Wang and X. Hui, Org. Chem. Front., 2020, Advance Article , DOI: 10.1039/D0QO00423E

Social activity

Search articles by author

Spotlight

Advertisements