Jump to main content
Jump to site search


Ni-Catalyzed electrophile driven regioselective arylative cyclization of ortho-functional diaryl acetylenes for the synthesis of pyridine and indene derivatives

Author affiliations

Abstract

A regioselective carbonickelation followed by cyclization, an arylative cyclization, of ortho functional diaryl acetylenes is achieved apparently through an electrophile driven alkyne polarization. A series of selectively substituted di aryl isoquinoline, pyridine and indene derivatives are thus accessed from diarylacetylenes with azide, carbonyl and cyanide tethers.

Graphical abstract: Ni-Catalyzed electrophile driven regioselective arylative cyclization of ortho-functional diaryl acetylenes for the synthesis of pyridine and indene derivatives

Back to tab navigation

Supplementary files

Publication details

The article was received on 15 Oct 2019, accepted on 15 Nov 2019 and first published on 18 Nov 2019


Article type: Research Article
DOI: 10.1039/C9QO01266D
Org. Chem. Front., 2020, Advance Article

  •   Request permissions

    Ni-Catalyzed electrophile driven regioselective arylative cyclization of ortho-functional diaryl acetylenes for the synthesis of pyridine and indene derivatives

    M. K. R. Singam, A. Nagireddy, M. Rajesh, V. Ganesh and M. S. Reddy, Org. Chem. Front., 2020, Advance Article , DOI: 10.1039/C9QO01266D

Search articles by author

Spotlight

Advertisements