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Issue 1, 2020
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Cu-catalyzed C–N bond cleavage of 3-aminoindazoles for the C–H arylation of enamines

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Abstract

The Cu-catalyzed C–H arylation of enamines via the oxidative C–N cleavage of 3-aminoindazoles is presented. A diverse array of arylated enamines were produced in decent yields with a wide substrate scope under mild conditions. Here, 3-aminoindazoles were harnessed as novel arylating agents via a radical process.

Graphical abstract: Cu-catalyzed C–N bond cleavage of 3-aminoindazoles for the C–H arylation of enamines

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Article information


Submitted
24 Sep 2019
Accepted
24 Oct 2019
First published
01 Nov 2019

Org. Chem. Front., 2020,7, 25-29
Article type
Research Article

Cu-catalyzed C–N bond cleavage of 3-aminoindazoles for the C–H arylation of enamines

Y. Zhou, Y. Wang, Z. Song, T. Nakano and Q. Song, Org. Chem. Front., 2020, 7, 25
DOI: 10.1039/C9QO01177C

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