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Issue 2, 2020
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Dynamic covalent polymers for biomedical applications

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Abstract

The rapid development of supramolecular polymer chemistry and constitutional dynamic chemistry over the last decades has made tremendous impact on the emergence of dynamic covalent polymers. These materials are formed through reversible covalent bonds, endowing them with adaptive and responsive features that have resulted in high interest throughout the community. Owing to their intriguing properties, such as self-healing, shape-memory effects, recyclability, degradability, stimuli-responsiveness, etc., the materials have found multiple uses in a wide range of areas. Of special interest is their increasing use for biomedical applications, and many examples have been demonstrated in recent years. These materials have thus been used for the recognition and sensing of biologically active compounds, for the modulation of enzyme activity, for gene delivery, and as materials for cell culture, delivery, and wound-dressing. In this review, some of these endeavors are discussed, highlighting the many advantages and unique properties of dynamic covalent polymers for use in biology and biomedicine.

Graphical abstract: Dynamic covalent polymers for biomedical applications

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Article information


Submitted
25 Sep 2019
Accepted
26 Nov 2019
First published
03 Dec 2019

Mater. Chem. Front., 2020,4, 489-506
Article type
Review Article

Dynamic covalent polymers for biomedical applications

Y. Zhang, Y. Qi, S. Ulrich, M. Barboiu and O. Ramström, Mater. Chem. Front., 2020, 4, 489
DOI: 10.1039/C9QM00598F

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