Jump to main content
Jump to site search

Issue 2, 2020
Previous Article Next Article

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

Author affiliations

Abstract

Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential for the treatment of injury and disease. These biomaterials are widely used in the tissue engineering field due to their ability to support cell proliferation, migration and differentiation, to permit oxygen and nutrient transport, and to mimic native soft tissue. Careful design of the underlying polymer scaffold is therefore vital, dictating both the physical and biological properties of a hydrogel. In this review, we will provide a critical overview of hydrogel design from the perspective of the polymer chemistry, highlighting both the advantages and limitations of particular polymer structures, properties, and architectures. In doing so, we will help equip researchers with the tools needed to design new polymer systems and hydrogel scaffolds that address current limitations in the field and hinder clinical translation.

Graphical abstract: Hydrogel scaffolds for tissue engineering: the importance of polymer choice

Back to tab navigation

Article information


Submitted
10 Jul 2019
Accepted
19 Sep 2019
First published
25 Sep 2019

Polym. Chem., 2020,11, 184-219
Article type
Review Article

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

C. D. Spicer, Polym. Chem., 2020, 11, 184
DOI: 10.1039/C9PY01021A

Social activity

Search articles by author

Spotlight

Advertisements