Jump to main content
Jump to site search


Hydrogel scaffolds for tissue engineering: the importance of polymer choice

Author affiliations

Abstract

Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential for the treatment of injury and disease. These biomaterials are widely used in the tissue engineering field due to their ability to support cell proliferation, migration and differentiation, to permit oxygen and nutrient transport, and to mimic native soft tissue. Careful design of the underlying polymer scaffold is therefore vital, dictating both the physical and biological properties of a hydrogel. In this review, we will provide a critical overview of hydrogel design from the perspective of the polymer chemistry, highlighting both the advantages and limitations of particular polymer structures, properties, and architectures. In doing so, we will help equip researchers with the tools needed to design new polymer systems and hydrogel scaffolds that address current limitations in the field and hinder clinical translation.

Graphical abstract: Hydrogel scaffolds for tissue engineering: the importance of polymer choice

Back to tab navigation

Publication details

The article was received on 10 Jul 2019, accepted on 19 Sep 2019 and first published on 25 Sep 2019


Article type: Review Article
DOI: 10.1039/C9PY01021A
Polym. Chem., 2020, Advance Article

  •   Request permissions

    Hydrogel scaffolds for tissue engineering: the importance of polymer choice

    C. D. Spicer, Polym. Chem., 2020, Advance Article , DOI: 10.1039/C9PY01021A

Search articles by author

Spotlight

Advertisements