Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.



Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers

Author affiliations

Abstract

In this study, we report for the first time the use of four aza-dipyrromethenes (ADPMs) as photosensitizers for cancer PDT. The synthesis and characterization of the ADPMs and their photodynamic action against B16F10 melanoma cells were assessed. ADPM 2 is the best singlet oxygen generator and the most phototoxic (at 2.5 μM) towards B16F10 cells.

Graphical abstract: Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers

Back to tab navigation

Supplementary files

Article information


Submitted
26 Mar 2020
Accepted
18 May 2020
First published
19 May 2020

Photochem. Photobiol. Sci., 2020, Advance Article
Article type
Paper

Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers

K. A. D. F. Castro, L. D. Costa, S. Guieu, J. C. Biazzotto, M. D. G. P. M. S. Neves, M. A. F. Faustino, R. S. da Silva and A. C. Tomé, Photochem. Photobiol. Sci., 2020, Advance Article , DOI: 10.1039/D0PP00114G

Social activity

Search articles by author

Spotlight

Advertisements