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Organophosphorus compounds are important structural motifs that unveil enormous applications, particularly in the field of organic synthesis, agriculture, materials science and medicinal chemistry. Additionally, ortho-substituted arylphosphorus compounds have played an important role in homogeneous catalysis. Though there are several synthetic pathways for the synthesis of organophosphorus compounds, this review is particularly focused on aryne-based methodologies reported in the literature to date.

Graphical abstract: Recent advances in the synthesis of organophosphorus compounds via Kobayashi's aryne precursor: a review

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