Intermolecular fluoroamination of allenes towards substituted vinyl fluorides†
Abstract
A synthetic method towards fluorinated allylamines using allene precursors is reported. A variety of heterocyclic amines were employed as nucleophiles in a Selectfluor promoted intermolecular fluoroamination reaction. This strategy provides a novel synthetic route to access vinyl fluorides with a vicinal amine moiety.
- This article is part of the themed collection: Synthetic methodology in OBC