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Issue 39, 2020
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Cu(i)/sucrose-catalyzed hydroxylation of arenes in water: the dual role of sucrose

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Abstract

A protocol for the hydroxylation of aryl halides catalyzed by copper(I) and sucrose in neat water has been developed. The dual role of sucrose, the reaction pathway, and the high selectivity for hydroxylation were investigated using a combination of experimental and theoretical techniques.

Graphical abstract: Cu(i)/sucrose-catalyzed hydroxylation of arenes in water: the dual role of sucrose

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Article information


Submitted
14 Aug 2020
Accepted
17 Sep 2020
First published
17 Sep 2020

Org. Biomol. Chem., 2020,18, 7827-7831
Article type
Communication

Cu(I)/sucrose-catalyzed hydroxylation of arenes in water: the dual role of sucrose

K. Watanabe, M. Takagi, A. Watanabe, S. Murata and R. Takita, Org. Biomol. Chem., 2020, 18, 7827
DOI: 10.1039/D0OB01683G

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