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Issue 38, 2020
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Cobalt-catalyzed carbonylation of the C–H bond

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Abstract

Direct carbonylation of the C–H bond is a great tool for installing a carbonyl group in a wide variety of substrates. This review summarizes the C–H bond carbonylation methodologies using the cobalt-catalyzed C–H bond functionalization approach. Despite the fact that cobalt-catalyzed carbonylation methodologies have been known since Murahashi's report in 1955, this area is still underdeveloped, particularly carbonylation of the C(sp3)–H bond.

Graphical abstract: Cobalt-catalyzed carbonylation of the C–H bond

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Article information


Submitted
07 Aug 2020
Accepted
25 Aug 2020
First published
16 Sep 2020

Org. Biomol. Chem., 2020,18, 7460-7466
Article type
Review Article

Cobalt-catalyzed carbonylation of the C–H bond

L. Lukasevics and L. Grigorjeva, Org. Biomol. Chem., 2020, 18, 7460
DOI: 10.1039/D0OB01633K

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