Ziyang Wang, Anqi Huang, Fang Fang, Pengfei Li, Guokai Liu and Wenjun Li
Org. Biomol. Chem., 2020,18, 6807-6811
DOI:
10.1039/D0OB01558J,
Communication
An efficient DBU-catalyzed conjugate addition of 5H-oxazol-4-ones to o-hydroxyphenyl-substituted p-quinone methides has been developed, affording the valuable diarylmethanes in high yields with excellent diastereoselectivity. This strategy demonstrates a robust access to a wide range of diarylmethane derivatives possessing biologically significant o-hydroxyphenol and p-hydroxyphenol moieties under mild reaction conditions.