Takumi Abe and Seiya Hirao
Org. Biomol. Chem., 2020,18, 4193-4197
DOI:
10.1039/D0OB01038C,
Communication
One-pot synthesis of indole-fused bicyclo[2.2.2]octanones from DiMeOIN and 2-cyclohexen-1-one is accomplished under an iodine catalyst. The simple and metal-free conditions provide a practical tool to construct Csp3-rich complex molecules via coupling cyclization.