Yong You, Bao-Xue Quan, Zhen-Hua Wang, Jian-Qiang Zhao and Wei-Cheng Yuan
Org. Biomol. Chem., 2020,18, 4560-4565
DOI:
10.1039/D0OB00979B,
Communication
A catalyst-free and controllable reaction of isatin-derived para-quinone methides with sulfur ylides was developed. This protocol enables the divergent synthesis of two different valuable oxindole derivatives with a broad substrate scope and high stereoselectivities (up to >20 : 1 dr and only the (Z)-configuration).