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Silver-catalyzed direct C–H oxidative carbamoylation of quinolines with oxamic acids

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Abstract

A silver-catalyzed efficient and direct C–H carbamoylation of quinolines with oxamic acids to access carbamoylated quinolines has been developed through oxidative decarboxylation reaction. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance and excellent yields under mild conditions.

Graphical abstract: Silver-catalyzed direct C–H oxidative carbamoylation of quinolines with oxamic acids

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Article information


Submitted
18 Feb 2020
Accepted
21 Mar 2020
First published
23 Mar 2020

Org. Biomol. Chem., 2020, Advance Article
Article type
Paper

Silver-catalyzed direct C–H oxidative carbamoylation of quinolines with oxamic acids

J. Yuan, Q. Chen, C. Li, J. Zhu, L. Yang, S. Zhang, P. Mao, Y. Xiao and L. Qu, Org. Biomol. Chem., 2020, Advance Article , DOI: 10.1039/D0OB00358A

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