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Issue 21, 2020
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Recent advances in the synthesis of imidazoles

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The review highlights the recent advances (2018-present) in the regiocontrolled synthesis of substituted imidazoles. These heterocycles are key components to functional molecules that are used in a variety of everyday applications. An emphasis has been placed on the bonds constructed during the formation of the imidazole. The utility of these methodologies based around the functional group compatibility of the process and resultant substitution patterns around the ring are described, including discussion of scope and limitations, reaction mechanisms and future challenges.

Graphical abstract: Recent advances in the synthesis of imidazoles

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Article information

17 Feb 2020
11 May 2020
First published
18 May 2020

Org. Biomol. Chem., 2020,18, 3950-3964
Article type
Review Article

Recent advances in the synthesis of imidazoles

D. A. Shabalin and J. E. Camp, Org. Biomol. Chem., 2020, 18, 3950
DOI: 10.1039/D0OB00350F

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