Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 14, 2020
Previous Article Next Article

Direct synthesis of ortho-methylthio allyl and vinyl ethers via three component reaction of aryne, activated alkene and DMSO

Author affiliations

Abstract

A synthetic strategy has been developed for the direct synthesis of ortho-methylthio allyl and vinyl ethers via three-component reaction of in situ generated aryne, activated alkene and DMSO. This reaction proceeds via several bond cleavage and bond formation processes in a single operation. Mechanistic studies reveal that DMSO served as both a methylthiolating agent and an oxygen source. This synthetic method provides a wide range of ortho-methylthio-substituted arenes in good yields.

Graphical abstract: Direct synthesis of ortho-methylthio allyl and vinyl ethers via three component reaction of aryne, activated alkene and DMSO

Back to tab navigation

Supplementary files

Article information


Submitted
07 Feb 2020
Accepted
20 Mar 2020
First published
20 Mar 2020

Org. Biomol. Chem., 2020,18, 2727-2738
Article type
Paper

Direct synthesis of ortho-methylthio allyl and vinyl ethers via three component reaction of aryne, activated alkene and DMSO

H. Hazarika and P. Gogoi, Org. Biomol. Chem., 2020, 18, 2727
DOI: 10.1039/D0OB00275E

Social activity

Search articles by author

Spotlight

Advertisements