Issue 7, 2020

Automated access to well-defined ionic oligosaccharides


Ionic polysaccharides are part of many biological events, but lack structural characterisation due to challenging purifications and complex synthesis. Four monosaccharides bearing modifications not found in nature are used for the automated synthesis of a collection of ionic oligosaccharides. Structural analysis reveals how the charge pattern affects glycan conformation.

Graphical abstract: Automated access to well-defined ionic oligosaccharides

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Article information

Article type
21 Jan 2020
04 Feb 2020
First published
04 Feb 2020
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2020,18, 1349-1353

Automated access to well-defined ionic oligosaccharides

Y. Zhu, T. Tyrikos-Ergas, K. Schiefelbein, A. Grafmüller, P. H. Seeberger and M. Delbianco, Org. Biomol. Chem., 2020, 18, 1349 DOI: 10.1039/D0OB00137F

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