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Issue 7, 2020
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Automated access to well-defined ionic oligosaccharides

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Abstract

Ionic polysaccharides are part of many biological events, but lack structural characterisation due to challenging purifications and complex synthesis. Four monosaccharides bearing modifications not found in nature are used for the automated synthesis of a collection of ionic oligosaccharides. Structural analysis reveals how the charge pattern affects glycan conformation.

Graphical abstract: Automated access to well-defined ionic oligosaccharides

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Article information


Submitted
21 Jan 2020
Accepted
04 Feb 2020
First published
04 Feb 2020

This article is Open Access

Org. Biomol. Chem., 2020,18, 1349-1353
Article type
Communication

Automated access to well-defined ionic oligosaccharides

Y. Zhu, T. Tyrikos-Ergas, K. Schiefelbein, A. Grafmüller, P. H. Seeberger and M. Delbianco, Org. Biomol. Chem., 2020, 18, 1349
DOI: 10.1039/D0OB00137F

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