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NBD-based fluorescent probes for separate detection of cysteine and biothiols via different reactivities

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Abstract

NBD-based fluorescent probes that can separately detect cysteine and biothiols via different reactivities have been rationally designed and synthesized. The probes can be applied to kinetically distinguish cysteine from other biothiols at 30 min, and to detect all biothiols at 3 h in living cells.

Graphical abstract: NBD-based fluorescent probes for separate detection of cysteine and biothiols via different reactivities

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Article information


Submitted
08 Jan 2020
Accepted
11 May 2020
First published
11 May 2020

Org. Biomol. Chem., 2020, Advance Article
Article type
Communication

NBD-based fluorescent probes for separate detection of cysteine and biothiols via different reactivities

H. Huang, X. Ji, Y. Jiang, C. Zhang, X. Kang, J. Zhu, L. Sun and L. Yi, Org. Biomol. Chem., 2020, Advance Article , DOI: 10.1039/D0OB00040J

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