Qingfeng Xu, Bang Li, Yujie Ma, Fei Sun, Yanan Gao and Na Ye
Org. Biomol. Chem., 2020,18, 666-670
DOI:
10.1039/C9OB02489A,
Paper
A metal-free K2S2O8-HFIP synergistically promoted double Friedel–Crafts alkylation between a glycine derivative and N-substituted aniline was developed to efficiently synthesize diarylmethane derivatives with high para-selectivity. The reaction proceeded smoothly in the absence of any metal and ligand, and exhibited a good tolerance of functional groups.
