The effect of spermidine on guanine decomposition via photoinduced electron transfer in DNA†
Spermidine, a trivalent organic cation, induced DNA structural changes and suppressed guanine photooxidative decomposition via electron transfer through pyrene-modified DNA. On the other hand, adding higher concentrations of spermidine resulted in DNA condensation. The efficiency of guanine decomposition in condensed pyrene-modified DNA was promoted remarkably.
- This article is part of the themed collection: Chemical biology in OBC